EO in mice exposed to constant concentrations of ET at target concentrations between 1 and 10 000 ppm. A, Time courses of EO in blood at the end of exposures lasting up to 6h. Each data point for which an error bar (+ or – SD) is given represents a mean value obtained in 3 animals. Each other data point was obtained with 1 animal. Lines connect means and individual data points, respectively. B, Time courses of EO in the air of closed chambers (2.8 l) each were containing 5 animals during one 6-h exposure. Each data point for which an error bar (± SD) is given represents a mean value obtained in 3 exposures to the same target concentration. Each other data point was measured during 1 experiment at a given target concentration. There were 3 exposures to 30 ppm ET and 2 exposures to 10, 3, or 1 ppm ET. Lines connect the mean values. In the nonexposed control group, EO concentrations were below the limit of detection. Abbreviations: EO, ethylene oxide; ET, ethylene.