Fig. 4.
Effects of Known ER Agonists and Antagonists on ERβ-Coactivator Interaction A, The ability of known ER agonists (E2 and diethylstilbestrol) to induce an interaction between ERα and SRC-1 was tested following methods described in the legend to Fig. 2. B, The effects of known ER antagonists (4-OH-tamoxifen and clomiphene) on E2-induced ERα-SRC-1 interaction were analyzed in the presence of 1.5 nm E2 (6 × EC50). The experiment was repeated three times with similar results.
