Variability in specific antibiotic use practices across Ontario acute care hospitals. In these funnel plots, variability in antibiotic use practices (y-axes) are plotted against total hospital PDs in 2014 (x-axes). Each circle represents an individual hospital and shading denotes hospital type. Each plot examines a unique antibiotic use practice: (a) the proportion of all antibiotics that were broad-spectrum (carbapenems, fluoroquinolones, glycopeptides, oxazolidinones, penicillin and β-lactamase inhibitor combinations, third-generation cephalosporins); (b) the proportion of oral respiratory antibiotics (respiratory fluoroquinolones and macrolides) that were respiratory fluoroquinolones; (c) the proportion of oral urinary anti-infectives (ciprofloxacin, nitrofurantoin, trimethoprim/sulfamethoxazole) that were ciprofloxacin; (d) the proportion of all antibiotics that were high-risk for C. difficile infection (clindamycin, fluoroquinolones, third-generation cephalosporins); (e) the proportion of all antibiotics that were ‘reserved-use’ (daptomycin, ertapenem, linezolid, meropenem); and (f) the proportion of antibiotics with Gram-negative coverage (aminoglycosides, second- and third-generation cephalosporins, fluoroquinolones, colistin, carbapenems, piperacillin/tazobactam, trimethoprim/sulfamethoxazole) that were anti-pseudomonal (aminoglycosides, ceftazidime, ciprofloxacin, colistin, meropenem, piperacillin/tazobactam).