Figure 2.
Glis3 inactivation in adult mice drastically reduces insulin expression in the islets. Immunostaining of Ins and Gcg in the pancreas of Glis3fl/fl/RosaCreERT2 mice at 4 weeks after vehicle (A) or TAM (B, C) treatment. Representative images of 4 fluorescent sections (approximately every 10th section) processed from 4 independent pancreata for each genotype. Scale bar, 20 μm.

Glis3 inactivation in adult mice drastically reduces insulin expression in the islets. Immunostaining of Ins and Gcg in the pancreas of Glis3fl/fl/RosaCreERT2 mice at 4 weeks after vehicle (A) or TAM (B, C) treatment. Representative images of 4 fluorescent sections (approximately every 10th section) processed from 4 independent pancreata for each genotype. Scale bar, 20 μm.

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