Association between BMI reduction and microbiome abundance. The x-axis represents the logarithmic abundance of microbial genera identified by HiFIT in Fig. 6a. The y-axis represents the reduction in BMI following bariatric surgery. We also include the association between age and BMI reduction as a reference. The smoothing curves and 95% confidence bands are obtained by locally polynomial regression. The color of the curves represents the number of HiFIT models in Fig. 6a identifying the feature as significant.