Figure 4.
Depletion of eosinophils blocked Alt+PNE-induced increases in IL-33 and OSM but not Areg. iPhil+/− FT+/− pups were treated as described in Fig. 2A. Pups plasma at 4 h after gavage were measured by ELISAs for levels of (A) IL-33, (B) OSM, and (C) Areg. (A) *P < 0.05 compared groups without asterisks. +P < 0.05 compared to saline group. (B) *P < 0.05 compared to all groups. (C) *P < 0.05 compared to indicated groups. Alt, Alternaria Alternata extract; Areg, amphiregulin; DTX, diphtheria toxin; IL-33, interleukin 33; OSM, oncostatin M; PNE, peanut extract.

Depletion of eosinophils blocked Alt+PNE-induced increases in IL-33 and OSM but not Areg. iPhil+/− FT+/− pups were treated as described in Fig. 2A. Pups plasma at 4 h after gavage were measured by ELISAs for levels of (A) IL-33, (B) OSM, and (C) Areg. (A) *P < 0.05 compared groups without asterisks. +P < 0.05 compared to saline group. (B) *P < 0.05 compared to all groups. (C) *P < 0.05 compared to indicated groups. Alt, Alternaria Alternata extract; Areg, amphiregulin; DTX, diphtheria toxin; IL-33, interleukin 33; OSM, oncostatin M; PNE, peanut extract.

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