COCOA predicts compartment patterns for epigenomic perturbation experiments

The row where green “No perturbation” (reference) indicates the comparison between the predicted CM and the experimental CM (ground truth) for the unperturbed data. Red, black, and blue labels in the vertical axis indicate high, medium, and low impact of the perturbed epigenomic signals on the chromatin compartment patterns, respectively. A. Proportion of compartment pattern matching between the predicted CM and the experimental CM from the one-perturbation epigenomic combinations. B. Proportion of compartment pattern matching between the predicted CM and the experimental CM from the two-perturbation epigenomic combinations.