Differentially abundant taxa and microbial pathways in Crohn’s disease (CD) vs control phagocytes. A and B, Heat maps, based on z-scores, display significantly (FDR P-value < .05) differentially abundant taxa present in more than half of samples in either group (n = 10 CD, n = 5 control). Each column represents a separate sample, and samples are grouped by diagnosis (CD vs control). A, Ileal samples with differentially abundant taxa at the species and family levels. B, Colon samples with differentially abundant taxa at the species level (no taxa at the family level were significant). C and D, Gene Ontology (GO) biological functions enriched in CD vs control samples from (C) the ileum (n = 10 CD vs n = 5 control) and (D) the colon (n = 11 CD vs n = 9 controls), plotted based on the log2 fold change between groups. *FDR-adjusted P-value < .05. FDR, false discovery rate; ns, not significant.
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