Intraocular Implant Scenario: (a) Efficacy function, white stars denote $dopt,k$⁠, (b) expected sample size and expected number of unique doses evaluated, (c) expected dose units from the optimal dose combination as defined in (6) by iteration, (d) average RPSEL as defined in (7) by iteration, and (e) average absolute deviation of the posterior mean estimate by iteration. On the x-axis in (b), P stands for personalized and S for standard, followed by the number referring to high replication for a smaller number of doses (1) or low replication for a larger number of doses (2).