Scenario 3. (a) Efficacy function, white stars denote $dopt,k$⁠, (b) expected dose units from the optimal dose combination as defined in (6) by iteration, (c) average RPSEL as defined in (7) by iteration, and (d) average absolute deviation of the posterior mean estimate by iteration. In (b), the plot for $(z1=0,z2=0)$ is empty as no optimal dose combination exists.