Figure 1.
![BiTE structure consists of two scFvs; a set of heavy and light chain variable regions targeting a TAA (VHA and VLA) linked via a peptide chain to a set of heavy and light chain variable regions targeting CD3ε (VHB and VLB) [14]. There are no Fc regions. Fab antigen binding fragment, Fv variable fragment, Fc fragment crystallizable, mAb monoclonal antibody. Created with BioRender.com](https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/immunotherapyadv/5/1/10.1093_immadv_ltae005/1/ltae005_fig1.jpeg?Expires=1749561084&Signature=l8VXohxBSra1-Q2~FeaPmbNqHN~g4p7ADihn2pJO~cloW3nj9hagJ-NBJSVJxkvdLeZQSnF4XMwWLXadP9Zay0mwZiaSl4eBD6R2TYWgoB6~Per217Cm9LGVuXtu99ZGYNAKjR0r938B9FPMRwhXPbgfIynlKvHfpA4ybnGvuJ5IwRS8ZWwQRxGX2IjjGiMHqm~heEVW1oh1AfwWfH8sM~8jAa6GkW0WDU8SNqzinvfvg0pgFbeDyoWr4b~r5PJRbRULkKEPNvWsI6Ym0iJd5gz-zdHb3fOWa-v2JjyOxonVWKkepNcdYUmafS3seYIoK65dG869MZ2hp034DYPNUw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
BiTE structure consists of two scFvs; a set of heavy and light chain variable regions targeting a TAA (VHA and VLA) linked via a peptide chain to a set of heavy and light chain variable regions targeting CD3ε (VHB and VLB) [14]. There are no Fc regions. Fab antigen binding fragment, Fv variable fragment, Fc fragment crystallizable, mAb monoclonal antibody. Created with BioRender.com
