Comparison of oak microbial isolates obtained by agar plating and dilution-to-extinction and the endogenous oak microbial community analysed by a culture-independent approach. (A) Unifrac distance between bacterial isolates characterized by 16S rRNA gene profiling and the bacterial fraction of the endogenous oak microbiota, (B) Unifrac distance between fungal isolates characterized by ITS profiling and the fungal fraction of the endogenous oak microbiota, (C and D) number of bacterial and fungal ASVs, respectively, detected in oak microbial isolates obtained by agar plating and dilution-to-extinction and ASVs detected by culture-independent analysis of the oak microbiota.