Comparison in the ROC profiles between Optim-GRAMMAR and the four competing methods. The ROC profiles are plotted using the statistical powers to detect QTNs relative to the given series of Type I errors. Here, the simulated phenotypes are controlled by 200 QTNs with the low, moderate and high heritabilities in human and maize. The ROC profiles for all simulated phenotypes are reported in Supplementary Figure 2S.