Association of folate/folic acid supplementation status and AD-GRS for AD risk. The multivariable model was adjusted for age, sex, BMI, TDI, education, ethnicity, assessment center, healthy diet, iron supplementation, smoking, alcohol, history of hypertension, cardiovascular disease, diabetes, stroke, and the levels of TG, HDL-C, LDL-C, and CRP. The vertical line indicates a reference value of 1. AD = Alzheimer’s disease; AD-GRS = AD genetic risk score; BMI = body mass index; CI = confidence interval; CRP = C-reactive protein; HDL-C = high-density lipoprotein cholesterol; HR = hazard ratio; LDL-C = low-density lipoprotein cholesterol; TDI = Townsend deprivation index; TG = triglycerides.