Analysis of colon cells with PoincaréDMT. (A) The developmental hierarchy as suggested by Ding et al. [27]. (B) Rotation of PoincaréDMT with respect to a randomly picked up root cell from the stem cell type. (C) PoincaréDMT pseudotime. (D) Statistics of embedding quality metrics |$Q_{global}$|, |$Q_{local}$| and average silhouette width across multiple patient origin batches for colon epithelial cells. (E) Embeddings produced by PoincaréDMT for colon immune cells, T cells and B cells. (F) Statistics of embedding quality metrics across multiple patient origin batches for colon immune cells.