The projections of cells using the different methods based on CITE-seq data. (A) Cell types are distinguished by scMMAE, Scanpy, scMM, SCOIT, and TotalVI. The blue, red, orange, and purple circles highlight B cells, T cells, myeloid cells, and natural killer cells. (B-C) Expression of marker genes CD4 and CD8A for CD4 and CD8 T cells. (D) Expression of marker gene ITGAM for myeloid cells. (E) Expression of marker gene JCHAIN for B cells. (F) scMMAE can distinguish CXCL8+ and CXCL8- macrophage.