Similar rescue of Dis3 depletion in the germline is observed when hDIS3  |$\mathbf{and}$|hDIS|${\mathbf{3}}^{\boldsymbol{p.H}\mathbf{774}\boldsymbol{Y}}$|  are driven via nanosGAL4. Both hDIS3|$\mathrm{and}$|hDIS|${3}^{p.H774Y}$| similarly rescue dDis3 when driven via germline driver nanosGAL4. This can be seen in the similar structure and arrangement of ovarioles and egg chamber development shown in A-F. There is no significant increase in S7-8 egg chamber degradation in hDIS|${3}^{p.H774Y}$| when compared to hDIS3 (G), ns = 0.5655, error bars indicate standard deviation, hDIS3 n = 9 ovaries, hDIS|${3}^{p.H774Y}$| n = 11 ovaries