MiR-5195-3p regulates ECM metabolism in fibroblasts of vaginal wall tissues in patients with pelvic organ prolapse. Note: (A) Immunofluorescence analysis of vimentin, keratin, and α-SMA expression in fibroblasts; (B) immunoblotting assessment of ECM metabolism–related protein expression in cells; (C) immunofluorescence evaluation of ECM metabolism–related protein expression in cells. (^* indicates a significant difference compared to the control group, P < 0.05; ^# indicates a significant difference compared to the POP + inhibitor NC group, P < 0.05.)