Total a), coding b) and non-coding c) genome size variation, and final coding fraction d), after 2 million generations. For each of the 5 WTs, 10 replicas were performed under a constant population size (⁠$N0=1,024$ individuals) with 3 different mutation rates: the control $μ0=10−6$ mutations per base pair for each type of mutation, $4×μ0$ and $16×μ0$⁠.