Cardiovascular phenotype of foetal and adult offspring of obese pregnancy in human and pre-clinical animal models. Maternal obesity induces cardiac hypertrophy,^{30,37,38,48,52,54,57,58,104} arterial remodelling,⁵³ and systolic and diastolic dysfunction^{38,104,44,48,49,52,57–59,61,70} in the foetal offspring, leading to sympathetic dominance,^{21,22,36,42,47,56,59,61,70} endothelial dysfunction^{16,17,36,42,56,85}, and hypertension^{79–82,13,18,22,28,29,36,46,53,72–76,86} in post-natal life. Key publications supporting statements are cross-referenced. Created with BioRender.com