Colitis-induced gut microbiota dysbiosis in WT and octn1^-/- mice. Panel A: Shannon index box plots calculated on gut microbiota of octn1^-/- and WT animals in presence or not of DSS induced colitis. P value, corrected for FDR, has been obtained by Kruskal-Wallis test. Panel B: PCoA plot of Bray Curtis dissimilarity matrix of octn1^-/- and WT genotypes in presence or not of DSS induced colitis. P value has been computed by PERMANOVA test. Panel C: Relative abundance of the indicated phyla by mouse strain and experimental treatment. Comparisons among the 4 groups (octn1^-/- and WT with or without DSS) were by DESeq2 statistics.