Histopathological comparison of labial and parotid salivary gland biopsies. Focus score (A), relative area of CD45⁺ infiltrates (B), CD20⁺ B lymphocytes (C) and CD3⁺ T cells (D) in SjD and non-SjD sicca patients and the number of Bcl6⁺ GCs per mm² (E) and the maximum severity of LELs (F) in salivary gland sections of only SjD patients. LEL stage 0: pre-LEL, lymphocytic infiltration without ductal hyperplasia; LEL stage 1: lymphocytic infiltration with ductal hyperplasia affecting <50% of the epithelium; LEL stage 2: lymphocytic infiltration with ductal hyperplasia affecting 50–100%; LEL stage 3: lymphocytic ductal infiltration and fully circumferentially hyperplastic epithelium without lumen.^*P < 0.05, ^***P ≤ 0.001. SjD: Sjögren’s disease; LEL: lymphoepithelial lesion