Post-implant anti-thrombotic therapy and rates of device-related thrombus. (A) Post-implant anti-thrombotic regimens used in multicentre clinical registries and device-related thrombus rates dependent on patient risk and physicians’ preference. (B) Different schemes of post-implant anti-thrombotic therapy according to patients’ risk profile. DAPT, dual antiplatelet therapy; DOAC, direct oral anticoagulants; DVT, device-related thrombus; SPT, single antiplatelet therapy.