Representative PSR-stained heart sections of 8-week-old animals. Jup-KO mouse heart displays extensive fibrosis and myocardial atrophy (A). WT control mouse heart tissue without fibrosis, representing the aspect of a healthy heart with normal collagen content (B). Stitched overviews. Scale bars: 1000 μm. Rectangles represent zoomed inlays. Abbreviations: See Fig. 1.