OCT matching frames (top row) are shown from before and after the implantation of the device (pre- and post-DREAMS 3G), at 6 and 12 M for two different patients; the top one experienced late lumen enlargement and the bottom LLL. The corresponding frames analysed by the OCTPlus software are shown in the relevant bottom rows. These frames depict the colour coding used for the different tissue types. The frame after the implantation is not presented because the struts produce an artefact that it is misinterpreted by the software. Of note, at the top example, the lesion (top left frame) was severely calcified and further modified with the predilation and device implantation. On the top row, the frames show resorption and full integration of the device into the vessel wall at 6 and 12 M. On the same example bottom row, please note the new layer of fibrous tissue (green) overlying the calcium and other constituents of the plaque. The second example showing LLL (compare lumen size between post-DREAMS 3G and 12 M) had a more fibrotic plaque before the intervention. Please note that all the blue circles superimposed to the OCT catheter are of the same size.