Risk estimation using the EuroSMR risk score. The Figure demonstrates the likelihood for 1-year mortality (black line) after mitral valve transcatheter edge-to-edge repair with increasing EuroSMR risk scores. The red and blue lines depict the likelihood for the combined clinical endpoints at 1-year follow-up of ‘mortality or New York Heart Association class IV’ (red line) and ‘mortality or New York Heart Association class ≥III’ (blue line). The relative distribution of EuroSMR risk score values in the extended EuroSMR registry is displayed on top of the figure. M-TEER, mitral valve transcatheter edge-to-edge repair; NYHA, New York Heart Association