Amyloid and tau status in the cohort. (A) Aβ/tau status in the included participants from ADNI. Aβ positivity was established using ADNI’s tracer-specific recommendations for both florbetapir and florbetaben. Tau positivity was defined as having at least one region positive for tau pathology (spatial extent index of one and above). (B) Scatterplot of the probability of having at least one positive tau region (i.e. spatial extent index equal to or higher than one) as a function of the Aβ load (in centiloid). The probability was extracted from a logitistic regression. The odds ratio (and confidence interval) derived from a logistic regression is presented at the bottom of the graph. Note that the points were jittered by a factor of 0.065 × 0.065 for visualization purposes.