Heatmap showing Spearman correlations between circulating leptin and various circulating cytokines and cytokines produced by ex vivo stimulation of PBMCs in 302 obese individuals, either in the entire cohort or in subgroups, indicated on the horizontal axis. Spearman correlation was performed, and data are presented divided in columns for all individuals, men, and women with and without MetS. Cells colored in red indicate a positive correlation and in blue indicate a negative correlation. Age- and false discovery rate–corrected data, *P < 0.05, **P < 0.01.