Comparison of human iNKT cells from thymus and peripheral blood. (A) UMAP plot of scRNA-seq data showing distinct clusters of human iNKT cells from thymus and peripheral blood. (B) Stacked plots indicating the proportions of different iNKT cell clusters in samples from human thymus and peripheral blood. (C, D) Relative expression and normalized counts of SOX4 (C) and KLRB1 (D) in human iNKT cell clusters depending on the tissue origin. (E) Bivariable heatmap representing the percentage (circle size) and the intensity (circle color) of expression of genes reflecting iNKT cell development and differentiation depending on the cluster and the tissue origin.