Four trajectories of estimated glomerular filtration rate (eGFR) based on serum creatinine levels and risk of all-cause mortality. (A) The survival part of the model is corrected for age at baseline, sex and Rotterdam Study cohort; (B) additionally adjusted for body mass index, smoking, alcohol use, cholesterol, triglycerides, hypertension, history of cardiovascular disease and diabetes. Cumulative incidences are plotted for the mean of covariates for continuous covariates and the reference category for categorical covariates