Ketamine effects on functional connectivity of the thalamus hub network (analysis 1). Each period of 2.5 minutes is depicted. Interaction effects drug*time of posthoc t tests are displayed and data overlaid on a standard-MNI brain. Warm colors stand for increase of connectivity and cold colors for decreased connectivity, while color intensity refers to t-values (range t=3.09…6). A significant increase is shown in temporo-parietal regions throughout the ketamine application. x=-58mm, y=-16mm.