Final recovery of LVDP (expressed as a percentage of the baseline value) and the dose-recovery changes in the hearts subjected to the preliminary study. Values are presented as the means of 6 hearts/group ± standard deviation. Control, no treatment; DMSO: 10 min of 0.1% DMSO perfusion; Esax: esaxerenone (10 min of esaxerenone perfusion at concentrations of 0.01, 0.1 and 1.0 μmol/l); LVDP: left ventricular developed pressure.