Viral RNA levels in blood, oral/rectal swabs, and nasal washes of infected ferrets. (A) Whole blood, (B) oral swabs, (C) rectal swabs, and (D) nasal washes were collected from each animal at 3, 5, 7, 10, and 14 days postinfection (dpi) as well as at time of euthanasia to evaluate viremia and viral shedding by reverse-transcription quantitative polymerase chain reaction. Results are depicted in genome equivalents per mL (GEQ/mL) for each animal (indicated by a square, triangle, or circle), with mean values depicted by a line.