Case-control analysis of biological aging and breast cancer status. Results from multivariable linear regression models treating the biological aging metric at the second timepoint as the dependent variable and breast cancer status as an independent variable. Referent group was the women who remained breast cancer–free. Models adjusted for baseline age, baseline biological aging metric, follow-up time, and race. CI = confidence interval; DunedinPACE = Dunedin Pace of Aging Calculated from the Epigenome; GrimAgeAccel = Age acceleration based on the GrimAge epigenetic clock; PhenoAgeAccel = Age acceleration based on the PhenoAge epigenetic clock.