A, Changes in mRNA expression levels of Nrf-2 (a), Ho-1 (b), Nqo-1 (c), Gstm (d), Mt-1 (e), Txnd1 (f), Txnl (g), Sod-1 (h), and Gstm-5 (i) in the cerebral cortex of wild-type and IL-1β KO mice exposed to acrylamide at 0, 12.5, 25 mg/kg bw for 28 days. Data are individual value plots and bars for mean ± SD (n = 6 per group). B, The extent of Nrf2 activation using ELISA test in the cerebral cortex of wild-type and IL-1β KO mice exposed to acrylamide at 0, 12.5, 25 mg/kg bw for 28 days. Data are individual value plots and bars for mean ± SD (n = 6 per group). *p < .05, **p < .01 compared with the corresponding genotype control (by Dunnett’s multiple comparison following ANOVA).