Subgroup analyses of Allergan Cheek Skin Smoothness Scale responder rates at Month 1 in the mITT population. The figure shows the binomial proportion difference between VYC-12L responders and no-treatment control responders at Month 1 for the overall mITT population and for each subgroup. Responder rate was defined as a ≥1-grade improvement in the ACSS score on both cheeks from baseline to Month 1. N1 = number of participants with data at baseline and Month 1 of control period. Horizontal bars in figure indicate 95% CI. ACSS, Allergan Cheek Skin Smoothness Scale; CI, confidence interval; mITT, modified intent-to-treat; NTC, no-treatment control.