(A) Representative example of an average sonR cycle composed of 15 consecutive, ensemble-averaged cycles (B). The same average sonR cycle, high-pass filtered, and its envelope in doted gray line. The vertical markers are the detected components of sonR1 and sonR2, including, consecutively (1) tsonR1_onset, (2) tsonR1_end, (3) tsonR2_onset, and (4) tsonR2_end. t = 0, the onset of the cardiac cycle, is the pacing artefact or the QRS onset marker. (C) Average electrocardiographic signal composed of 15 consecutive, ensemble-averaged cycles.