Scatterplots of urine proteins significantly increased (top) and decreased (bottom) in JDM patients vs HC. Data are presented as mean ± SEM. **P ≤ 0.001, *P < 0.05. CTSD: cathepsin D (adj P = 0.001); LGALS3BP: galectin-3 binding protein (adj P = 0.02); SHISA5: protein shisa-5 (adj P = 0.02); COL1A1: collagen alpha-1 (I) chain (adj P = 0.01); COL2A1: collagen alpha-1(II) chain (adj P = 0.001); COL12A1: collagen alpha-1(XII) chain (adj P = 0.04); NPX: normalized protein expression; HC: healthy control