Voxel-wise fALFF and LCOR contrasts of patients with Huntington’s disease relative to their respective healthy controls. In a number of clusters where fALFF was significantly reduced in manifest Huntington’s disease of the first (A and B) or second (C and D) cohort, and LCOR significantly higher in manifest Huntington’s disease. Left panels: the atrophy-uncorrected contrasts; right panels: the atrophy-corrected contrasts. Anatomical regions covered by clusters and the MNI coordinates of the voxel with the peak t-value are listed in Supplementary Tables 2 and 3.