Morbidity in patients with mild autonomous cortisol secretion (MACS). ¹This is a summary figure of our systematic review.⁶⁹²MACS was defined by a serum cortisol after 1 mg dexamethasone >1.8 µg/dL and the results were compared to patients with nonfunctioning incidentaloma. ³For vertebral fractures an association was found in few studies when a cutoff of 3 µg/dL is used. ⁴Including microfractures.