Figure 5
Docking visualization of LRRK2 protein and its interacting proteins. (A) LRRK2 protein structure, the central protein LRRK2 (as the receptor) is displayed by default when the mPPI plugin interface is opened. (B) Select a docking protein TAU (as a ligand), the docking structure is displayed on the right, and the docking protein list on the left is updated accordingly, showing the compatibility or competition of each docking protein with the current structure. (C) A compatible multiprotein docking complex of Tau and 1433E protein. (D) A partial view of the domain of LRRK2 showing atomic details of its docking site with Tau protein. A cross-section view highlights the Phe residue of the amino acid chain of LRRK2 and the CD1 atom position. Phe: Phenylalanine; 2ZEJ: PDB identifier of LRRK2 structure; CD1: atomic position identifier.

Docking visualization of LRRK2 protein and its interacting proteins. (A) LRRK2 protein structure, the central protein LRRK2 (as the receptor) is displayed by default when the mPPI plugin interface is opened. (B) Select a docking protein TAU (as a ligand), the docking structure is displayed on the right, and the docking protein list on the left is updated accordingly, showing the compatibility or competition of each docking protein with the current structure. (C) A compatible multiprotein docking complex of Tau and 1433E protein. (D) A partial view of the domain of LRRK2 showing atomic details of its docking site with Tau protein. A cross-section view highlights the Phe residue of the amino acid chain of LRRK2 and the CD1 atom position. Phe: Phenylalanine; 2ZEJ: PDB identifier of LRRK2 structure; CD1: atomic position identifier.

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