Progression-free survival (PFS) and overall survival (OS) (N = 28). (A) Arm A (N = 10) median PFS was 4.8 months (95% CI 2.8, NA); (B) Arm B (N = 12) median PFS was 3.9 months (95% CI 2.8, NA); (C) Arm C (N = 6) median PFS was 8.2 months (95% CI 4.6, NA); (D) Arm A (N = 10) median OS was 11.2 months (95% CI 7.2, NA); (E) Arm B (N = 12) median OS was 17.0 months (95% CI 9.5, NA); and (F) Arm C (N = 6) median OS was NA (95% CI 11.1, NA). PFS, progression-free survival; OS, overall survival; NR, not reached.