Figure 6
Real-time-polymerase chain reaction results of genes associated with metabolism (Ucp3, Acaa2, Pfkfb1) signaling, mitochondrial-localized kinases (Sbk3), cardiac function (Mir133a-2), apoptosis (C920009B18Rik), hypoxia (lox), and interstitial remodeling (postn). Chromonar restored or partially restored the expression of C920009B18Rik, Postn, Lox, Ucp3, and Sbk3 but did not alter the expression of Mir133a-2, Acaa2, or Pfkb1. Data are mean ± 95% CI (n = 4–5 per group). *P < 0.05 vs. corresponding Kv1.5−/−-control group; # P < 0.05 vs. corresponding Kv1.5−/−-transaortic constriction (Takotsubo syndrome) group. The data were analyzed by a one-way ANOVA followed by Šídák’s multiple comparison test. ANOVA, analysis of variance; CI, confidence interval.

Real-time-polymerase chain reaction results of genes associated with metabolism (Ucp3, Acaa2, Pfkfb1) signaling, mitochondrial-localized kinases (Sbk3), cardiac function (Mir133a-2), apoptosis (C920009B18Rik), hypoxia (lox), and interstitial remodeling (postn). Chromonar restored or partially restored the expression of C920009B18Rik, Postn, Lox, Ucp3, and Sbk3 but did not alter the expression of Mir133a-2, Acaa2, or Pfkb1. Data are mean ± 95% CI (n = 4–5 per group). *P < 0.05 vs. corresponding Kv1.5−/−-control group; # P < 0.05 vs. corresponding Kv1.5−/−-transaortic constriction (Takotsubo syndrome) group. The data were analyzed by a one-way ANOVA followed by Šídák’s multiple comparison test. ANOVA, analysis of variance; CI, confidence interval.

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