Enrichment plots of gene expression associated with pathways of fatty acid metabolism (left), oxidative phosphorylation (middle), and hypoxia (right). Comparisons were made between control Kv1.5−/− and those subjected to transaortic constriction exhibiting Takotsubo syndrome. Genes associated with the pathways of fatty acid metabolism and oxidative phosphorylation were downregulated in Takotsubo syndrome (vs. control), but the pathway associated with hypoxia was upregulated in Takotsubo syndrome. n = 2 per group.