Accuracy of H3K4me3 log-posterior odds score compared with H3K4me3 filtering in mES cells. Results are shown for predicting the binding sites of 13 TFs in mES cells. Accuracies are measured using peak-centric gold standards. The solid bars represent the mean sensitivity at 1% false positive rate; error bars show standard error. ‘PWM’ refers to using just the PWM score; ‘Prior’ refers to the log-posterior odds score using the H3K4me3 prior; ‘≥n’ refers to the H3K4me3 histone-filtering method using a tag-count threshold of n.