Graph of tacrolimus trough levels. The line graph showed the initial tacrolimus trough level prior to Paxlovid therapy followed by subsequent trough levels after completing therapy while on tacrolimus. The final value illustrates the resolution in toxicity after holding tacrolimus. The July 5th value was the final trough level on the day of discharge. The patient's last tacrolimus level at our facility was 4 months prior to his admission and was normal. Paxlovid was used from 6/22 to 6/27. This is the revised document with marked changes noted in either bold or underlined (as in the Legends section). In addition, the citations used were included in superscript within the body of the Discussion section.