ECG findings of DCM patients with arrhythmic genotypes. First ECG evidence of asymptomatic slow atrial fibrillation in 48 years-old female with a familiar history of SCD carrying likely pathogenic mutation in LMNA gene (A). Basal ECG of a 33 years-old man with a missense mutation in LMNA gene (p.Arg190Trp) displays signs of septal remodelling, such as pathological Q waves in leads V1–V4, poor R-wave progression (R wave <3 mm) in leads V1–V3 and QRS fragmentation. Extremely low QRS voltages in precordial leads, diffuse flat T waves, premature ventricular beats with LBBB, and inferior axis morphology are also present (B). A 51-year-old man with FLNC mutation and familiar history of DCM shows on ECG negative TWI in infero-lateral leads (C). ECG performed in 61-year-old man with a PLN p.Arg14del mutation. The ECG shows very low QRS voltages in limb leads, flat T waves, and poor R wave progression in precordial leads (D). DCM, dilated cardiomyopathy; FLNC, filamin C; LBBB, left bundle branch block; LMNA, lamin A/C; LV, left ventricular; PLN, phospholamban; SCD, sudden cardiac death; TWI, T wave inversion.