Behavioural analyses for the three cognitive domains. (A) The violin wrapping box-and-whisker plots of all z-transformed outcome variables included in the study. The width of the violins represents the proportion of patients with an equivalent z-value. The overall median z-values are indicated by the horizontal white line in each box-and-whisker plot. Each box represents the lower (Q1) to the upper (Q3) quartiles, with whiskers extending from the minimum to the maximum of 1.5 times the interquartile range. The number of available patient datasets for each variable is depicted at the bottom of each violin. Outliers are depicted by grey circles. Blue represents outcome variables typically measuring visuospatial attention (Letter Cancellation Tests = Letter CoC; Line Bisection Test = LB; CoC in the Five-Point Test = FPT CoC; mean gaze position during FVE), yellow represents outcome variables typically measuring alertness (TAP phasic alertness = phasic Alert; TAP tonic alertness = tonic Alert; mean fixation duration during FVE = FVE fix dur; peak saccade velocity during FVE = FVE peak vel), grey represents outcome variables typically measuring inhibition (percentage of perseverative errors in the Five-Point Test = FPT Persev; Go-NoGo paradigm of the FAB = Go-NoGo; errors in the Stroop Interference condition = STROOP; antisaccade errors = Antis). (B) The significant correlations between all 12 variables included in the PCA. The lines between variables represent significant correlations and their strength: the darker the shade, the stronger the correlation, as represented by the legend on the right-hand side of the panel. (C) The principal components extracted from outcome variables of the cognitive domains of visuospatial attention, alertness and inhibition, with factor loadings >0.40. The length of the bars represents the loading of each outcome variable onto the extracted factor components. The components were named as follows: Component 1 = common component; Component 2 = inhibition/alertness component; Component 3 = alertness component. The figure was illustrated using the R package ggplot2.^159,160