Design and outcome of studies assessing the efficacy of intravascular imaging in predicting events. ACS, acute coronary syndrome; AS, area stenosis; CFD, computational fluid dynamics; DS, diameter stenosis; FCT, fibrous cap thickness; IB, integrated backscatter; IVUS, intravascular ultrasound; LCBI, lipid core burden index; maxLCBI_4mm, maximum LCBI in 4 mm segment; MI, myocardial infarction; MLA, minimum lumen area; NIRS, near-infrared spectroscopy; NPV, negative predictive value; OCT, optical coherence tomography; PAV, per cent atheroma volume; PB, plaque burden; PCI, percutaneous coronary intervention; PPV, positive predictive value; RI, remodelling index; TCFA, thin-cap fibroatheroma; UA, unstable angina; VH, virtual histology; WSS, wall shear stress.