Figure 5.
Expression of HLA-DR and granzyme B on Eomesodermin (Eomes) and Tbet-expressing subsets of Mycobacterium tuberculosis (Mtb)-specific IFNγ+CD4+ T cells 2 weeks on antiretroviral therapy (ART). (A) Expression of HLA-DR and (B) granzyme B on Eomes and Tbet subsets (Eomes−, Tbet+, Eomes+, Tbet+, Eomes−, Tbet++ and Eomes+, Tbet++) of Mtb-specific IFNγ+CD4+ T cells in TB-IRIS (red, n = 5), and non-IRIS patients (black, n = 4), 2 weeks on ART. The Mann-Whitney U test was used for statistical comparison of unpaired samples. Only statistically significant data with a P value of .05 or less are indicated on graphs.